The most popular shows for "Special Guest Star":
| What | Why | Votes |
| Scrubs | Special Guest Star (Clay Aiken) | 626 |
| Gilligan's Island | Special Guest Star (the Harlem Globetrotters) | 529 |
| Supernatural | Special Guest Star ( Linda Blair) | 503 |
| Howard Stern | Special Guest Star (Cabbie) | 490 |
| The Simpsons | Celebrity Guest Stars | 440 |
| Arrested Development | Special Guest Star (Charlize Theron) | 411 |
| Will & Grace | Special Guest Stars (too many of them) | 344 |
| Sex and the City | Not That There's Anything Wrong With It (Samantha and Special Guest Star Sonia Braga) | 340 |
| The O.C. | Special Guest Star (Paris Hilton) | 292 |
| The Simpsons | Special Guest Star (Britney Spears) | 278 |
| Heroes | Special Guest Star (Stan Lee) | 276 |
| The Simpsons | Special Guest Star ('NSync) | 272 |
| The Simpsons | Special Guest Star (Kid Rock) | 253 |
| Scrubs | Special Guest Star (Heather Locklear) | 247 |
| The Simpsons | Special Guest Star (J. K. Rowling) | 234 |
| That 70's Show | Special Guest Star (Roger Daltrey) and the Rock Opera | 221 |
| Scooby Doo | Special Guest Stars (real people) | 217 |
| The Simpsons | Special Guest Star (Matt Groening) | 214 |
| The Oprah Winfrey Show | Special Guest Star (Dr. Phil) | 208 |
| The Simpsons | Special Guest Star (Tony Blair) | 204 |
| The Simpsons | Special Guest Star (Alec Baldwin) | 190 |
| CSI: Crime Scene Investigation | Special Guest Star (Kevin Federline) | 173 |
| Family | Special Guest Star (Leif Garrett) | 168 |
| The Simpsons | Special Guest Star (Tony Hawk) | 164 |
| Punk'd | Special Guest Star (Britney Spears) tries to rap | 130 |
| American Idol | Special Guest Star (George W. and Barbara Bush) | 130 |
| Dharma & Greg | Special Guest Star (Kevin Sorbo) | 129 |
| Star Trek - Voyager | Special Guest Star (The Rock) | 125 |
| The Simpsons | Special Guest Star (Liz Taylor as Maggie) | 124 |
| Miami Vice | I Do (Crockett and Special Guest Star Sheena Easton) | 122 |
| Sex and the City | Special Guest Star (Mikhail Baryshnikov) | 108 |
| 7th Heaven | Special Guest Star (Jewel) | 101 |
| Arrested Development | Special Guest Star (Martin Short) | 101 |
| 30 Rock | Special Guest Star - Jerry Seinfeld | 98 |
| Boston Legal | Special Guest Star (Al Sharpton) | 92 |
| Star Trek - Voyager | Special Guest Star (Jason Alexander) | 91 |
| Star Trek - Voyager | Special Guest Star (Andy Dick) | 91 |
| The O.C. | Special Guest Star (George Lucas) | 86 |
| Alvin and the Chipmunks | Special Guest Star (Mr. T) | 85 |
| The Simpsons | Special Guest Star (Mandy Moore) | 79 |
| Las Vegas | Special Guest Star (Paris Hilton) | 78 |
| The Simpsons | Special Guest Star (Mel Gibson) | 76 |
| Full House | Special Guest Star (The Beach Boys) | 74 |
| Hope & Faith | Special Guest Star (Regis) | 73 |
| Two and a Half Men | Special Guest Stars (Sean Penn and Elvis Costello) | 71 |
| Dallas | Special Guest Star (Joel Grey) | 69 |
| Scrubs | Special Guest Star (Tara Reid) | 67 |
| That 70's Show | Special Guest Star (Jessica Simpson) | 66 |
| ALF | Special Guest Star (Jm J) | 65 |
| CSI: NY | Special Guest Star (Kid Rock) | 63 |
| The Simpsons | Special Guest Star (Paul McCartney) | 63 |
| Buck Rogers in the 25th Century | Special Guest Star (Gary Coleman) | 62 |
| WCW Nitro | Special Guest Stars | 61 |
| Lost | Special Guest Star (Cheech Marin) | 60 |
| The Simpsons | Special Guest Star (Helen Hunt) | 58 |
| The Arsenio Hall Show | Special Guest Star (Bill Clinton plays the sax) | 57 |
| How I Met Your Mother | Special Guest Star (Wayne Brady) | 57 |
| The Facts of Life | Special Guest Star (Stacy Q) | 56 |
| Nip/Tuck | Special Guest Star (Rosie O'Donnell) | 56 |
| 7th Heaven | Special Guest Stars (The Olsen twins) | 55 |
| Dawson's Creek | Special Guest Star (Jack Osbourne) | 55 |
| Lost | Special Guest Star (Billy Dee Williams) | 53 |
| 3rd Rock From The Sun | Special Guest Star (William Shatner) | 53 |
| ER | Too many celebrity guest stars | 52 |
| The Odd Couple | Celebrity Special Guest Stars | 51 |
| The Simpsons | Special Guest Star (Poochie) | 51 |
| Smallville | Lame Special Guest Stars | 50 |
| Will & Grace | Special Guest Star (Madonna) | 50 |
| What's Happening!! | Special Guest Star (The Doobie Brothers) | 49 |
| Joan of Arcadia | Special Guest Star (Hilary Duff) | 48 |
| ER | Special Guest Star (Sally Field) | 47 |
| Gilligan's Island | Special Guest Stars (that made no sense) | 47 |
| The Simpsons | Special Guest Star (Johnny Cash) | 47 |
| Dirt | Special Guest Star (Jennifer Anniston) | 47 |
| The Facts of Life | Special Guest Star (El Debarge) | 45 |
| Dallas | Special Guest Star (Barbara Eden) | 45 |
| Just Shoot Me! | Special Guest Star (Tiffani Theissen) | 44 |
| Smallville | Special Guest Star (Christopher Reeve) | 41 |
| Full House | Special Guest Star (Scott Baio) | 40 |
| CBS Evening News | Special Guest Star (Rush Limbaugh) | 40 |
| Still Standing | Special Guest Star (Sally Struthers) | 39 |
| Boston Legal | Special Guest Star (Candice Bergen) | 39 |
| Smart Guy | Special Guest Stars (Tia and Tamara) | 38 |
| Smallville | Special Guest Star (Tom Wopat and the blue General Lee) | 37 |
| South Park | Special Guest Star (Mr. Hanky) | 37 |
| The Cosby Show | Special Guest Star (film stars and jazz musicians) | 37 |
| Deal or No Deal | Special Guest Star (Celine Dion) | 36 |
| Arthur | Special Guest Stars (The Backstreet Boys) | 36 |
| Monk | Snoop Dogg Raps the "here's what happened" | 36 |
| The O.C. | Special Guest Star (Linda Lavin) | 36 |
| The Fairly OddParents | Special Guest Star (Chip Skylark) | 35 |
| Sabrina - The Teenage Witch | Special Guest Star (Britney Spears) | 35 |
| Lizzie McGuire | Special Guest Star (Aaron Carter) | 35 |
| That 70's Show | Special Guest Star (Luke Wilson) | 35 |
| American Idol | Special Guest Star (Gwen Stefani) | 34 |
| 7th Heaven | Special Guest Star (Lance Bass) | 34 |
| Gilmore Girls | Special Guest Star (Madeline Albright) | 33 |
| 7th Heaven | Special Guest Star (Wayne Newton) | 33 |
| Sabrina - The Teenage Witch | Special Guest Star (Aaron Carter) | 32 |
| The Fresh Prince of Bel-Air | Special Guest Star (Tyra Banks) | 31 |
